Mid Delta Regional Airport is the only commercial airport located in the Delta.Located approximately three miles north of Greenville, MDRA is situated on 2,000 acres of land, with a sizable portion in the Mid-Delta Empowerment Zone. A controlled airfield, MDRA has a control tower which is manned from 7:00 a.m. to 7:00 p.m., seven days a week.

MDRA has two runways, the primary being 18L/36R. This runway is composed of an asphalt surface 150 feet wide by 8,001 feet long. It is a precision approach runway with an Instrument landing System (ILS), medium approach lighting system with rails, (MALSR) approach lights and High Intensity Runway Lights (HIRLs). A parallel runway, 18R/36L is a non-precision runways with a width of 150 feet and length of 7,019 feet with Medium Intensity Runway Lights, (MIRL). The runways are connected by six taxiways. Ramp space is abundant., with 2.66 million square feet of concrete ramp area, there is room to meet any need.